Science backs it up: 3 fruits that fight liver fat, regulate sugar and cholesterol

Non-alcoholic fatty liver disease (NAFLD), which affects 25-35% of adults according to the World Health Organization (2025), is a silent condition that can lead to inflammation, fibrosis, or cardiovascular problems if left unaddressed. Fat accumulation in the liver, along with sugar and cholesterol imbalances, is linked to diets high in processed sugars and fats.

However, nature offers powerful solutions: certain fruits, loaded with antioxidants, fiber, and bioactive compounds, can reverse these problems. Recent studies, such as one in Nutrients (2025), highlight that a diet rich in specific fruits reduces liver fat by 10-15% in 12 weeks.

Here, we explore three science-backed fruits—blueberries, apples, and avocados—that fight fatty liver disease, stabilize glucose, and improve cholesterol profiles, with ideas for including them in your daily routine and tips for a healthy approach.

Blueberries: Little Giants Against Fatty Liver Disease

Blueberries, with their vibrant color, are a nutritional treasure that goes beyond their flavor. Their richness in anthocyanins, a type of antioxidant, makes them an effective weapon against fatty liver disease and metabolic imbalances.

How They Work

A study in the Journal of Functional Foods (2025) showed that consuming 150 g of blueberries daily for 8 weeks reduced liver fat by 12% in patients with NAFLD, as measured by ultrasound. Anthocyanins inhibit lipogenesis (fat formation) and improve lipid oxidation in the liver. Additionally, they stabilize blood sugar by improving insulin sensitivity by 10%, according to Diabetes Care (2024), and lower LDL (“bad”) cholesterol by 7% thanks to their soluble fiber, according to Lipids in Health and Disease (2025).

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