Those with a BRCA2 mutation face up to a 69% risk of breast can.cer and a 17% risk of ovarian cancer.
These mutations can be inherited from either parent and are passed down in families. That’s why a family history of either ca.ncer can raise your own risk—even if no one in your family has had both.
Family History Matters
If your mother, sister, grandmother, or aunt has had breast or ovarian can.cer (especially at a young age), your own risk may be higher. This is true even if they had only one type. In some cases, multiple generations may be affected without knowing the cause was genetic.
Women with a strong family history may consider genetic counseling and testing for BRCA mutations. Knowing your genetic status can help you and your doctor make personalized decisions about prevention and screening.
Other Common Risk Factors
Besides genetics, breast and ovarian cancers share several other risk factors, including:
Age: Risk increases with age, especially after 50.
Hormone therapy: Long-term use of hormone replacement therapy (HRT) after menopause may increase the risk of both can.cers.
Reproductive history: Women who started menstruating early or experienced late menopause have slightly higher risks.
Never having children or having children later in life may also raise risk for ovarian ca.ncer.
How Knowing the Link Can Help
Understanding the link between breast and ovarian can.cer is important because it opens the door to preventive strategies:
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