Vitamin B12 is a nutrient the body can’t produce on its own, meaning you must obtain it from food or supplements. It’s especially important for energy production, red blood cell formation, and neurological health. Studies suggest that nearly 40% of North Americans are deficient in this essential vitamin, with rates even higher among those with conditions like Chronic Fatigue Syndrome or Fibromyalgia.
Testing for B12 Deficiency

Determining if you have a B12 deficiency isn’t always straightforward. While serum B12 tests are commonly used, they don’t measure how well your body is utilizing the vitamin. For a more accurate diagnosis, ask your doctor about an Intracellular B12 test. If that’s unavailable, tests for Methylmalonic Acid (MMA) and Homocysteine levels can offer additional insights.
What Causes a B12 Deficiency?

Several factors can lead to a deficiency in this vital nutrient:
Pernicious Anemia

This autoimmune condition damages stomach cells responsible for producing intrinsic factor, a protein needed for B12 absorption. Without intrinsic factor, your body struggles to absorb B12 from food, leading to a deficiency.